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Are you always hungry? Blame leptin resistance!
Many people mistakenly believe that gaining and losing weight depends solely on calories and willpower. However, this is not the case – experts say that one of the main factors contributing to weight gain in people is resistance to the hormone leptin. We decided to look into this issue and find out whether it is possible to make leptin work for weight loss.
Meet: leptin - the hormone-regulator of weight
Leptin is a hormone produced by the body’s fat cells. It is often called the hormone of satiety, satiety or starvation. The goal of leptin is the hypothalamus, reaching which, it tells the brain that it is time to stop fat accumulation, stop eating and start burning calories.
The primary function of leptin It is a long-term regulation of energy balance, the amount of calories consumed and expended, and the amount of fat stored in our body. It is worth noting that the saturation hormone also performs other functions related to reproductive function, immunity, brain function, etc.
The main purpose of leptin prevent starvation or overeating, which in certain conditions prevent a person from surviving in the natural environment. However, sometimes the mechanism that is designed to protect us from overeating fails.
What is the principle of the saturation hormone?
The principle of the saturation hormone is extremely simple: we eat, fat is deposited in fat cells, fat cells produce the hormone leptin, through the bloodstream it enters the brain and tells the hypothalamus that it is time to stop eating and start burning calories.
Or, we don’t eat, fat stores are burned, leptin levels are reduced, and as a result we eat more and burn fewer calories.
Is Leptin Resistance the Major Biological Cause of Obesity?
People with obesity have a large amount of fat in their fat cells, causing leptin levels to be elevated. Under normal conditions, the brain should know that there is no need to replenish fat stores. However, the problem arises: the brain simply does not see the huge amounts of leptin in front of its nose. This problem is called leptin resistance.
Resistance to saturation hormone causes the brain to think that the body lacks energy, leading to fat deposition.
As a result, the brain changes our physiology and behavior to make up for the perceived lack of fat.
How leptin nullifies the results of exhausting sitting on diets
Why do most diets fail to produce long-term results? Why is the long-term success of the diet not the rule, but the exception?
With weight loss, the body loses fat stores, which leads to a significant decrease in the level of saturation hormone, and this leads to a feeling of hunger, increased appetite, decreased motivation to exercise and burn fewer calories. The brain thinks that the body is starving, so it launches a bunch of powerful mechanisms aimed at replenishing fat loss and protecting against starvation. The brain tries its best to protect every fat cell and uses the overwhelming biochemical forces that make us eat.
Where does resistance to leptin come from?
Several cellular mechanisms underlying leptin resistance have been identified:
1. Inflammation – the inflammatory signals entering the hypothalamus – is one of the main causes of leptin resistance in both humans and animals.
2. Free fatty acids. Elevated levels of free fatty acids can prevent leptin signals from reaching the brain.
3. High levels of leptin.
Can leptin resistance be overcome?
The main fight against leptin resistance is to reduce inflammation caused by malnutrition. Here's what you can do:
1. Avoid processed foods – they are a major source of inflammation and compromise healthy digestion.
2. Eat soluble fiber – it helps protect against obesity and improves digestion.
3. Exercise – Physical activity helps increase leptin sensitivity.
4. Sleep – poor sleep leads to problems with the satiety hormone.
5. Reduce the number of triglycerides – high levels of triglycerides in the blood prevent leptin from entering the brain.
6. Eat protein – among other benefits, it will help improve leptin sensitivity.
Unfortunately, there is no simple way to lose weight. To get rid of fat deposits, you need to monitor your lifestyle: nutrition, sleep, physical activity. Remember that diet is a short-term solution to the problem of excess weight, to completely eliminate it, you need to significantly change your lifestyle. published
P.S. And remember, just changing our consumption – together we change the world!
Join us on Facebook, VKontakte, Odnoklassniki
Source: estet-portal.com/articles/interesnye-fakty/postoyanno-khochetsya-est-vinite-ustojchivost-k-leptinu
Meet: leptin - the hormone-regulator of weight
Leptin is a hormone produced by the body’s fat cells. It is often called the hormone of satiety, satiety or starvation. The goal of leptin is the hypothalamus, reaching which, it tells the brain that it is time to stop fat accumulation, stop eating and start burning calories.
The primary function of leptin It is a long-term regulation of energy balance, the amount of calories consumed and expended, and the amount of fat stored in our body. It is worth noting that the saturation hormone also performs other functions related to reproductive function, immunity, brain function, etc.
The main purpose of leptin prevent starvation or overeating, which in certain conditions prevent a person from surviving in the natural environment. However, sometimes the mechanism that is designed to protect us from overeating fails.
What is the principle of the saturation hormone?
The principle of the saturation hormone is extremely simple: we eat, fat is deposited in fat cells, fat cells produce the hormone leptin, through the bloodstream it enters the brain and tells the hypothalamus that it is time to stop eating and start burning calories.
Or, we don’t eat, fat stores are burned, leptin levels are reduced, and as a result we eat more and burn fewer calories.
Is Leptin Resistance the Major Biological Cause of Obesity?
People with obesity have a large amount of fat in their fat cells, causing leptin levels to be elevated. Under normal conditions, the brain should know that there is no need to replenish fat stores. However, the problem arises: the brain simply does not see the huge amounts of leptin in front of its nose. This problem is called leptin resistance.
Resistance to saturation hormone causes the brain to think that the body lacks energy, leading to fat deposition.
As a result, the brain changes our physiology and behavior to make up for the perceived lack of fat.
- We eat more;
- We're using less energy.
How leptin nullifies the results of exhausting sitting on diets
Why do most diets fail to produce long-term results? Why is the long-term success of the diet not the rule, but the exception?
With weight loss, the body loses fat stores, which leads to a significant decrease in the level of saturation hormone, and this leads to a feeling of hunger, increased appetite, decreased motivation to exercise and burn fewer calories. The brain thinks that the body is starving, so it launches a bunch of powerful mechanisms aimed at replenishing fat loss and protecting against starvation. The brain tries its best to protect every fat cell and uses the overwhelming biochemical forces that make us eat.
Where does resistance to leptin come from?
Several cellular mechanisms underlying leptin resistance have been identified:
1. Inflammation – the inflammatory signals entering the hypothalamus – is one of the main causes of leptin resistance in both humans and animals.
2. Free fatty acids. Elevated levels of free fatty acids can prevent leptin signals from reaching the brain.
3. High levels of leptin.
Can leptin resistance be overcome?
The main fight against leptin resistance is to reduce inflammation caused by malnutrition. Here's what you can do:
1. Avoid processed foods – they are a major source of inflammation and compromise healthy digestion.
2. Eat soluble fiber – it helps protect against obesity and improves digestion.
3. Exercise – Physical activity helps increase leptin sensitivity.
4. Sleep – poor sleep leads to problems with the satiety hormone.
5. Reduce the number of triglycerides – high levels of triglycerides in the blood prevent leptin from entering the brain.
6. Eat protein – among other benefits, it will help improve leptin sensitivity.
Unfortunately, there is no simple way to lose weight. To get rid of fat deposits, you need to monitor your lifestyle: nutrition, sleep, physical activity. Remember that diet is a short-term solution to the problem of excess weight, to completely eliminate it, you need to significantly change your lifestyle. published
P.S. And remember, just changing our consumption – together we change the world!
Join us on Facebook, VKontakte, Odnoklassniki
Source: estet-portal.com/articles/interesnye-fakty/postoyanno-khochetsya-est-vinite-ustojchivost-k-leptinu
