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Causes of cellulite: what you need to know
Currently, it is known that alpha - and beta-receptors located on adipocytes (fat cells) play a crucial role in the breakdown of fats (lipolysis), and that the formation and storage of fat (lipogenesis) depends on the efficiency of the binding of glucose and free fatty acids, and only impact on these key factors can contribute to the real resolution of such cosmetic problems as cellulite.
The adipocyte — continuously working "micromachines"
About 35 billion adipocytes form adipose tissue in women, which plays an essential role in the body, ensuring the maintenance of energy balance.
Due to the continuous activity, adipocytes provide your body with the necessary energy and store it for the future. The basis of this continuous activity are two processes with different, complementary mechanisms:
The imbalance between these two processes, lipogenesis and lipolysis, in addition to a number of other factors is the cause of cellulite.
In fact, excessive accumulation of fat leads to hypertrophy of adipocytes. As a result, a number of phenomena: compression of blood and lymphatic vessels, accompanied by water retention in the tissue; degeneration of collagen fibers, the result of which is the formation of the phenomenon of "orange peel".
In these manifestations played the role of many individual characteristics: heredity, period of hormonal changes (puberty, pregnancy, menopause, etc.), not exactly a balanced diet, sedentary lifestyle, stress.
KEY FACTORS DETERMINING THE PROCESS OF LIPOLYSIS: ALPHA - AND BETA-RECEPTORS.
On adipocytes represented by hormone receptors of two types, which govern the process of lipolysis: alpha - and beta-receptors. These two types of hormone receptors are under the control of appropriate hormones-catecholamines (epinephrine and norepinephrine) that can be active are two-fold:
Catecholamines have a more pronounced affinity for alpha-receptors and thus are able to communicate with them spontaneously. Moreover, often the women of the alpha-receptors predominate in the adipocytes located in the buttocks, thighs and inside the knees; this explains the fact that in adipocytes of these women antilipolytic activity largely dominates the lipolytic activity.
And only when all the alpha receptors are saturated, the corresponding hormones may be naturally in contact with the beta receptors and starts lipolysis. Key factors of lipogenesis: the combination of free fatty acids and glucose To lipogenesis it is necessary that through the membrane of the adipocyte penetrated free fatty acids and glucose, which serve as reagents for synthesis in fat cells as triglycerides. The accumulation of fat resulting in the adipocyte increases in volume (see Fig. below).
HOW TO INFLUENCE KEY FACTORS OF LIPOGENESIS AND LIPOLYSIS, AND THUS, THE CELLULITE.
The conclusion made from the review: it is possible to fight cellulite, provided that we act simultaneously on lipolysis and lipogenesis.
HOW?
-By taking drugs that block alpha — 2 receptors", with the aim of strengthening and stimulation of lipolysis.
Some molecules, which we refer to as "the alpha 2 — blocker", is able to quickly block the access of hormones to alpha-receptors, and thus inhibit their antilipolytic activity. Catecholamines are unable in this situation to get in contact with alpha receptors, and, thus, there is their natural binding to beta-receptors. The result aktiviziruyutsya lipolysis.
-By restriction of glucose into the body for the purpose of regulation of lipogenesis. In the absence of glucose, free fatty acids have nothing to communicate for the formation of triglycerides. Actually is limited by the formation and storage of fat.
PUBERTY (puberty): the CRITICAL PERIOD, WHICH SHOULD NOT be ignored
In accordance with the data of some authors the impression that every person born has a certain number of adipocytes. This initial volume of fat cells can develop until puberty, and then becomes constant.
Puberty is a critical period. When a girl becomes a woman, an equilibrium hormonal processes, the nature of which plays a decisive role in the formation of the volume of adipocytes. Under the influence of various factors, including hormonal, they can begin to hypertrophy.Thus, it is from this period begins to form excess fat, which ends with the appearance of cellulite.
Temporal tapping: disarmingly simple way to tune body, mind and soul
Stop criticize my body
It is also known that the appearance of cellulite is closely linked to a genetic predisposition: it is safe to say that the girl, whose mother suffers from cellulite, has a great chance to buy it.
Hence, it is very important to take all necessary preventive measures to avoid the formation of cellulite, starting from puberty, since the onset of puberty the body. published
Source: vk.com/wall-23903469?w=wall-23903469_676
The adipocyte — continuously working "micromachines"
About 35 billion adipocytes form adipose tissue in women, which plays an essential role in the body, ensuring the maintenance of energy balance.
Due to the continuous activity, adipocytes provide your body with the necessary energy and store it for the future. The basis of this continuous activity are two processes with different, complementary mechanisms:
- phase of lipogenesis, i.e. formation and storage of fats
- phase of lipolysis, ie fat breakdown.
The imbalance between these two processes, lipogenesis and lipolysis, in addition to a number of other factors is the cause of cellulite.
In fact, excessive accumulation of fat leads to hypertrophy of adipocytes. As a result, a number of phenomena: compression of blood and lymphatic vessels, accompanied by water retention in the tissue; degeneration of collagen fibers, the result of which is the formation of the phenomenon of "orange peel".
In these manifestations played the role of many individual characteristics: heredity, period of hormonal changes (puberty, pregnancy, menopause, etc.), not exactly a balanced diet, sedentary lifestyle, stress.
KEY FACTORS DETERMINING THE PROCESS OF LIPOLYSIS: ALPHA - AND BETA-RECEPTORS.
On adipocytes represented by hormone receptors of two types, which govern the process of lipolysis: alpha - and beta-receptors. These two types of hormone receptors are under the control of appropriate hormones-catecholamines (epinephrine and norepinephrine) that can be active are two-fold:
- antilipolytic action when they bind to alpha-receptors (see Fig. below)
- lipolytic action when they bind to beta-receptors (see Fig. below).
Catecholamines have a more pronounced affinity for alpha-receptors and thus are able to communicate with them spontaneously. Moreover, often the women of the alpha-receptors predominate in the adipocytes located in the buttocks, thighs and inside the knees; this explains the fact that in adipocytes of these women antilipolytic activity largely dominates the lipolytic activity.
And only when all the alpha receptors are saturated, the corresponding hormones may be naturally in contact with the beta receptors and starts lipolysis. Key factors of lipogenesis: the combination of free fatty acids and glucose To lipogenesis it is necessary that through the membrane of the adipocyte penetrated free fatty acids and glucose, which serve as reagents for synthesis in fat cells as triglycerides. The accumulation of fat resulting in the adipocyte increases in volume (see Fig. below).
HOW TO INFLUENCE KEY FACTORS OF LIPOGENESIS AND LIPOLYSIS, AND THUS, THE CELLULITE.
The conclusion made from the review: it is possible to fight cellulite, provided that we act simultaneously on lipolysis and lipogenesis.
HOW?
-By taking drugs that block alpha — 2 receptors", with the aim of strengthening and stimulation of lipolysis.
Some molecules, which we refer to as "the alpha 2 — blocker", is able to quickly block the access of hormones to alpha-receptors, and thus inhibit their antilipolytic activity. Catecholamines are unable in this situation to get in contact with alpha receptors, and, thus, there is their natural binding to beta-receptors. The result aktiviziruyutsya lipolysis.
-By restriction of glucose into the body for the purpose of regulation of lipogenesis. In the absence of glucose, free fatty acids have nothing to communicate for the formation of triglycerides. Actually is limited by the formation and storage of fat.
PUBERTY (puberty): the CRITICAL PERIOD, WHICH SHOULD NOT be ignored
In accordance with the data of some authors the impression that every person born has a certain number of adipocytes. This initial volume of fat cells can develop until puberty, and then becomes constant.
Puberty is a critical period. When a girl becomes a woman, an equilibrium hormonal processes, the nature of which plays a decisive role in the formation of the volume of adipocytes. Under the influence of various factors, including hormonal, they can begin to hypertrophy.Thus, it is from this period begins to form excess fat, which ends with the appearance of cellulite.
Temporal tapping: disarmingly simple way to tune body, mind and soul
Stop criticize my body
It is also known that the appearance of cellulite is closely linked to a genetic predisposition: it is safe to say that the girl, whose mother suffers from cellulite, has a great chance to buy it.
Hence, it is very important to take all necessary preventive measures to avoid the formation of cellulite, starting from puberty, since the onset of puberty the body. published
Source: vk.com/wall-23903469?w=wall-23903469_676
