In science fiction movies, we now and then see how the mortally wounded man rises to his feet, sprinkle magic spray from any spray. Before our eyes, it is regenerated tissue, wounds are tightened, as a result of the damage does not remain a trace. It seems that scientists from the Australian University of New South Wales in the coming years will be able to create a similar regeneration of human tissue system. Let it will not run as fast as in the movie, but its effectiveness has been proved experimentally.
The regeneration system is somewhat similar to the method by which a salamander grow a lost limb. It can be used for regeneration of bone structure, vertebral discs, as well as other tissues and organs.
Researchers see in his opening huge potential, because by this method it will be possible once and forever change the rules of the game for the benefit of mankind, defeating a variety of previously untreatable fatal diseases. The results of the research have been published by scientists in the journal Proceedings of the National Academy of Sciences.
Professor John Pimanda, managing research project, shared with readers of his team's discoveries. The new technology allows to reprogram the bone and fat cells, transforming them into induced multipotent stem cells (iMS). Initially, experiments were conducted on laboratory mice, and they showed excellent results compared with other therapies, the effectiveness of which either do not proven or extremely low. Trials of this technology in humans is planned for late 2017.
There are many types of stem cells, including embryonic, that during development of the embryo forming all the other cells of the human body. In adult organisms also have stem cells, but they can not regenerate any tissue, but only certain of its type. The revolutionary new technique is that the resulting iMS reprogramming cells are able to recover absolutely any tissue without causing terrible side effects such as the formation of tumors.
"The use of embryonic stem cells for the regeneration is unacceptable, as there is a risk of tumor formation. The second problem was that the old technique of forming stem cells involves the use of viruses for the transformation process, which is also acceptable from a medical point of view. With the new technology we have managed to overcome both of these obstacles, "- says one of the authors of the study, Dr. Your Chandrakantan
To create iMS scientists like cells "disable memory" bone and fat cells using analog key component of RNA and DNA is 5-azacytidine (AZA) and factor PDGF-AB growth, thereby turning them into stem. The process of conversion from start to finish in less than 3 weeks.
Thereafter, the resulting cells can be placed in the area of the human body tissue damage where they immediately start to general repair. In the future, this technology can solve many problems of modern medicine, including treatment of serious injuries, fatal diseases and even reverse the aging process handling.
Author: Sergey Gray