Russian scientists have created a cure for cirrhosis of the liver, previously considered incurable

Russian scientists from the Institute of Pharmacology of the Siberian Branch of the RAMS invented a substance that can deal with previously incurable disease - cirrhosis. This serious disease is among the ten leading causes of death of patients in many developed countries. Despite the fact that the liver is the only organ able to fully recover, there comes a time (when the body is already pretty "planted" and is the development of cirrhosis), when it is already impossible to restore.

Any physician will tell you that the liver is much harder to treat other organs, as the medicine is not yet fully understand the processes taking place in it.

Hourly passes through the liver about 90 liters of blood. Hazardous components entering the body, immediately neutralized, and the blood is flowing on. The liver is involved in the formation of a half of the whole body and lymph produced urea, it is a blood reservoir and depot vitamin B12, nicotinic acid and retinol. The liver contains a portion of the impact of iron and glycogen, which is at high energy costs is converted into glucose and acts as a spare battery.

In cirrhosis irreplaceable liver tissue regenerates in fibrous connective tissue, which has long been considered an irreversible process, because all existing drugs can only suspend it. And Novosibirsk pharmacists resulting 10-year study succeeded in using the technology to create a new synthesis of radiation substance - immobilized hyaluronate-endo-N-atsetilgeksozaminidaza (imGEAGA), which not only halts the process of fibrosis, but also stimulates liver regeneration. The mechanism of action is based on future drug stimulation of stem cells. It is known that the liver disease the body tries to restore it is by means of stem cells, which are both in the liver and in the kind of "Depot" - in the bone marrow. Stem cells are able to regenerate in any other, if necessary, are liver, "zalatyvaya" affected areas.

Now in Tomsk are preclinical studies of matter, after which the partners are scientists from the Novosibirsk company "Scientific Future Management" will start production of pilot batches of the new drug.

Source: Spark

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