Found the off button of pain

Scientists have found a new way to "disable" the pain, which can lead to drugs are not addictive. This should help people experiencing chronic discomfort.

The researchers were able to block the path of pain sensitivity in rodents with chronic neuropathic pain arising from damage to their nervous system. Activation of the receptor of type A3 in the brain and spinal cord of the rats have eliminated the unpleasant sensation of pain with an intense character.

Current methods of pain relief are far from perfect, as they cause intolerable side effects, diminish quality of life and not completely remove the pain. The new method is not addictive and is characterized by good tolerability in contrast to other pain-relieving drugs.

Researchers from Saint Luisago University in Missouri found that pain in rodents can be controlled via stimulation of the A3 receptor with adenosine (stimulator of natural origin) or synthetic compounds, with no side effects to the body. The results of the study were published in the medical journal Brain.

The strong analgesic effect of adenosine could provide a breakthrough in the treatment of chronic pain. Our study has shown that this can be achieved by stimulation of A3AR, says Daniela Salvemini, Professor of pharmacological and psychological Sciences from the University of St. Louis.

Chemical drug is considered by scientists as anti-inflammatory and antitumor agent.

Source: hi-news.ru