Made from cows "factory" for the production of human antibodies Bashny.Net

Cow with big sad eyes can serve as a factory for creating antibodies in large quantities. Scientists have placed a modified human chromosome into a cow to create antibodies to хантавируса. On the approach - working with Ebola virus and Middle East respiratory syndrome coronavirus.

The role of these "factories" for Ebola patients in the United States is now played by people develop immunity after the disease.






Antibodies, or immunoglobulins, are synthesized by lymphocytes in response to the invasion of foreign substances or organisms. For each of the "attack" of viruses need specific antibodies. Mankind is using someone else's antibodies to fight infectious diseases for over a hundred years. Since 1912, blood plasma had been ill flu patients transfused patient. Years later immune proteins saving people with Lassa fever, Ebola and SARS pnevponiey and other diseases.

The researchers took 14 and two human chromosomes containing genes for creating antibodies hantavirus, and combined them into an artificial chromosome, entered into a cow. Cows genes responsible for production of antibodies, are suppressed, so that they started to produce human immunoglobulins.

Hantaviruses were discovered in 1978. In Europe and Asia, infecting them manifest in mild form of haemorrhagic fever with renal syndrome, but there are deaths, four deaths were reported in the Krasnodar Territory in 2009.

Hantavirus in the cell membrane. I>





Source: geektimes.ru/post/242058/