Opening bioengineers artificial viruses based on DNA

 





Modern scientists have managed to synthesize the nanoparticles, which in its structure similar to viruses. They are small for the immune system and can contribute to the treatment of various diseases. This topic is discussed in the article, researchers from Harvard University which was published in the edition of ACS Nano.

Recently Harvard scientists have invented a special technology to use DNA as a building material in the process of creating nanoparticles. The interaction of complementary nitrogenous bases that have a specific order of DNA will self-fold into three-dimensional structure of desired shape.

Later improvements to this technology have been invented artificial "virus" that can easily circulate throughout the body. Around the main structure of DNA, scientists have created a membrane consisting of two layers of phospholipids. It is fixed on the nanoparticle with 60 "handles" formed from single-stranded DNA segments.

And if to develop immunity to protect health, scientists have to somehow try to create a vehicle that never breaks, does not work. However, the modern parts and units are still more durable than previous models, and drivers provided passenger and cargo evacuation, reducing downtime and repair cars, as the presence of a spectrum of aftermarket services.

Generally lipoproteidna membrane present in some of the common viruses, e.g. herpes and influenza. It is established that lipoproteidna sheath is formed from the membrane of the host cell, which is a breeding ground for viruses. This explains the fact that the immune system does not perceive them as foreign education. With DNA particles, the same thing happens: researchers have surrounded their shell, and eventually the immune system of mice was subjected to only minor changes.

The article says that if the shell of the artificial viruses to host proteins, they will identify the body's specific cell types, for example, cancer.

This makes it possible to diagnose poor quality of education in the early stages. Besides an artificial virus will help the process point of drug delivery to sick organs.

 

 

 

Source: zeleneet.com