New data confirm the impact of dirty air on autism and schizophrenia Bashny.Net

A study at the University of Rochester showed how air pollution early in life produces harmful changes in the brains of mice, in particular, those departments that are responsible for autism and schizophrenia.





Changes associated with autism and schizophrenia, occurred predominantly in males. Mouse also proved to be bad in the tests on short-term memory, learning ability and impulsivity. Doctor of medicine Deborah Cory-Šlechta says: "Our findings add to the growing list of evidence that air pollution may play a role in autism and other developmental disorders of the nervous system". In several experiments, Cory-Šlechta and her colleagues subjected mice to the effects of air pollution in different concentrations. Conducting impact during the first two weeks after birth, a critical time in brain development. Mice were exposed to polluted air for four hours each day for two four-day periods.

All had discovered mice inflammation throughout the brain and lateral ventricles — chambers on each side of the brain that contain cerebrospinal fluid — were enlarged two to three times compared to the normal size. "When we looked closely at the ventricles, we could see that the white matter that normally surrounds them, is not fully developed," said Cory-Šlechta. "It appears that inflammation had damaged those brain cells".

Problems were also observed in the second group of mice 40 days after exposure and in another group 270 days after exposure, indicating that the brain damage was permanent.In the brain of mice in all three groups, there were elevated levels of glutamate, a neurotransmitter that is present in humans with autism and schizophrenia.

Source: nauka24news.ru/