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Canadian scientists tested the anti-influenza drug that kills the virus and treat the patient
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The flu virus i>
Researchers from Canadian health care facilities, Sunnybrook Hospital and the Hospital of St. Michael, разработали fundamentally new drug , which should help in the fight against one of the most common diseases - influenza. The operating principle of the drug in some ways the opposite of traditional drugs.
Influenza - is an infectious viral disease. Its characteristic feature is the ability to rapidly mutate. Today has been known for more than 2,000 variants. The feasibility of vaccination against influenza is challenged on the grounds that at the time of the development of serum from a particular strain of the virus in the world already has a following of his choice. Therefore, the fight against epidemics of the disease very difficult.
Medicine knows this disease even in the 16th century. Over the past 150 years, there were 10 severe and very severe epidemics of influenza. For example, испанский Flu , or "Spanish flu" was the most massive flu pandemic in human history, in absolute terms, both the number of infected and dead. In 1918-1919, worldwide Spanish flu was infected about 550 million. People (almost 30% of the world population). Died by some estimates nearly 100 million. People (up to 5% of the population). The epidemic began in the last months of World War II and quickly surpassed the largest at the time of armed conflict on the scale of the victims.
Every year, according to the World Health Organization, the flu dies from an average 250 to 500 thousand people. But people do not die from the presence of the virus, and the complications that arise as a result of its activity in the body. One of the most common reasons for getting острый respiratory distress syndrome lungs. Inflamed blood vessels begin to miss жидкость, which penetrates into the alveoli, leading to asphyxia - a man suffocates.
While scientists are trying to keep up with the ever-changing strains of influenza, Dr. Warren Lee, a member of the research center of the hospital, thinking about the possibility of approaching the problem from the other side. What if, instead of trying to kill the virus, the body help itself? For example, to prevent damage to blood vessels and the subsequent leakage of fluid.
In the laboratory, two groups of mice were infected with influenza. One group received no treatment, and the second used an experimental drug Vasculotide, developed at Sunnybrook Hospital, firming эндотелий - Vessel walls. All the mice who did not receive the drug died. Among received the drug survived 80%.
At the same time, the drug worked, even when applied in a few days after infection, and does not adversely affect the immune response of the body. No side effects were observed when using the drug in tandem with antivirals.
Dr Lee is optimistic - although experiments were carried out on mice, symptoms occur in vertebrates almost identical, so most likely similar to drug or its variants can be tailored for people.
Source: geektimes.ru/post/251570/
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